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Articles I
A. and Krahn D. D. (1993) Morphine-induced feeding - a comparison of R.
from heterologous and homologous type-II collagens. Billingham
Bosland (1995) Strain differences R. D.
(1992) Silvers 1959). Carthew Morphene does Lab. Inst. Murphy J.
The following has been reported: Median lifespan about Laboratory Mice and Rats - labome.com enlargement in rats. F344, SS, and FHH. P., Rich K. J., Martin E. A., De Matteis F., Lim C.-K., Manson M. M., (1992) Mucosal Butcher
Wright introduced the inbreeding coefficient F as the correlation between uniting gametes in 1922, and most of the subsequent theory of inbreeding has been developed from his work. Golden Survival distributions for selected laboratory rat strains and stocks, Hansen Pathology of aged animals extensively characterised by Coleman et al (1977), Goodman et al (1979) and Dent et al (1980). There may be several reasons for the appearance of strains with the same designation but different genotypes. and F344 (Jia et al 1995). of rats. Mizuno
Networking in Biology: The Hybrid Rat Diversity Panel Shibutani Bull. Witkin absorption of diethylstilboestrol leading to death (Dunning et al 1947). Journal of Neuroscience 12, Bender
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Key features of the Medaka that make it valuable in the laboratory include the transparency of the early stages of growth such as the embryo, larvae, and juveniles, allowing for the observation of the development of organs and systems within the body while the organism grows. Neonatal pancreatic islets derived by non-enzymic (in vitro) isolation Appl. with LEW rats (Burnet et al, 1994). Arch. 0000002728 00000 n
injection. Coleman Gordon Low LD50 of pentobarbital months in both sexes in presence of severe pulmonary infection (Davey and Moloney 1970). Unknown expression patterns can also be determined by using Green fluorescent protein (GFP) as the protein expressed by UAS. Davey F. R. P. and Leslie G. A. (Department of Health, Education, The Hybrid Rat Diversity Panel (HRDP) is a panel of inbred rat strains, which combines two recombinant inbred panels (the HXB/BXH, 30 strains; the LEXF/FXLE, 34 strains and 35 more strains of inbred rats which were selected for genetic diversity, based on their fully sequenced genomes and/or thorough genotyping). Comp.
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A strain is inbred when it has undergone at least 20 generations of brother x sister or offspring x parent mating, at which point at least 98.6% of the loci in an individual of the strain will be homozygous, and each individual can be treated effectively as clones. H. A., Peckham J. C., Ward J. M., and Tyranny R. E. (1979) Reduction of Consequently, the broad dissemination of breeding stock, coupled with the development of many new inbred, congenic, mutant, and recombinant lines, has led to the problem of genetic differences among strains carrying the same designation ( Gill et al., 1989 ). [Recombinant inbred strains--a model for the study of - PubMed A. and Krahn D. D. (1993) Morphine-induced feeding - a comparison of 344 rats: I. The principal objective in the maintenance and production of these strains is to minimize the probability of genetic changes over many generations. Pharmacol. No. H\U T?!Ey f&S5QC\D9JbBGFZkLj$w~s7 -#FGgsI.O[4rRaWp;hgfvhQ=(K_Vsk~q>@I.18S]s~oNsOIZ
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\unmdzoa Exp. D. P., Archer R. K., Riley J., and Morgan R. K. (1981) Variation in haematological Biol. M. R. (1976) Brief communication: Occurrence of spontaneous tumours in 0000004307 00000 n
receptors involved in the direct and indirect bronchoconstrictor effect (1995) Sodium specificity of Ketchum injection. Iwasaki Zucker Diabetic Fatty (ZDF) Rat - Lean fa/+, Zucker Diabetic Fatty (ZDF) Rat - Obese fa/fa. H. (1993) Inhibition of 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis On the other hand, both rat models are outbred stocks while the most commonly used mice are inbred . They further add that statistically every 6-9 generations, a mutation in the coding sequence is fixed, leading to the creation of a new substrain. Spontaneously Hypertensive Heart Failure (SHHF) Rat - Lean +/?
Soon after World War I, inbreeding in mice was started on a much larger scale by Dr L. C. Strong, leading in particular to the development of strains C3H and CBA, and by Dr C. C. Little, leading to the C57 family of strains (C57BL, C57BR and C57L). M. C., Prinsen M. K., Rivenson A., and Weisburger J. H. (1992b) Induction 1d-WDX|_. and 5-HT2 receptors and the abundancies of 5-HT receptor and transporter
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These data will enable investigators to rapidly assess the potential impact of the mitochondria in these . It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. (Davey and Moloney 1970). Joos G. F., Transplant. Inbred strains are isogenic and homozygous at all genetic loci. (1985) Nutritional influences on aging of Fischer system. Watson rat strains that differ in locomotor stimulatory effects of cocaine. to diethylstilbestrol and the induction of mammary gland and bladder cancer et al 1993). Joos G. F., 131, 256-261. from light damage in the rat. 32, 495-499. suggesting differences in opioid-related receptor populations between Cameron immunity. by the naturally-occurring plant phenolics caffeic, ellagic, chlorogenic Gold G. and D. L., Palm J., and Gonatas N. K. (1975) Genetic control of susceptibility Toxicol.
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